Ultrasensitive quantification of serum IFN-α and IFN-γ in systemic lupus erythematosus: A cross-sectional observational study
by Miguel Á. González-Gay, Fuensanta Gómez-Bernal, Juan C. Quevedo-Abeledo, Cristina Almeida-Santiago, Elena Heras-Recuero, Arantxa Torres-Roselló, Antonia de Vera-González, Beatriz Tejera-Segura, Enrique García-Barrera, Teresa Blázquez-Sánchez, Luisa M. Villar, Javier Gonzalo Ocejo-Vinyals, Raquel Largo, Iván Ferraz-Amaro
BackgroundInterferon (IFN) has been implicated in the pathogenesis of patients with systemic lupus erythematosus (SLE). However, its measurement in serum has been limited by low circulating levels that fall below the detection threshold of standard laboratory assa...